A recent Yahoo News/YouGov poll showed that 20% of Americans say that they would refuse a a COVID-19 vaccine, and that an additional 26% are not sure if they would take it.
Among those who are unsure, or decidedly against receiving the vaccine, some fear that the vaccine will have been rushed and not been properly tested, others say they are skeptical about the effectiveness of a vaccine, considering how viruses mutate, and given the relative ineffectiveness of annual flu vaccines.
However, there are also some who are concerned about possibly nefarious motives by governments and influential people, such as Bill Gates.
The suspicion of a sinister conspiracy behind the development of a coronavirus vaccine has been spurred on by comments from Bill Gates on March 18, in which he said that in the future “digital certificates” could trace who had recently been tested or who had received a vaccine. The idea is that those who will have received the vaccine will be allowed to do things which those who refused the vaccine would not be allowed to do, such as shopping, working, and enjoying entertainment or recreation in certain places. By the next day, a rumor had begun circulating that these “digital certificates” would be a microchip which would be hidden in the vaccine. 
For some people, this sounded similar to what the Bible says in Revelation 13 about the Mark of the Beast, without which people will not be able to buy or sell, leading to fears that by receiving this vaccine, you might inadvertently receive the Mark of the Beast, which would lead to the loss of your soul.
What is the Mark of the Beast?
The Book of Revelation is a vision that the Apostle John had while in exile on the island of Patmos. In this vision he was instructed to write down the things that he had seen, the things that are, and those that are to take place in the future. (Revelation 1:19)
Revelation is written in the apocalyptic genre, which its interpretation has been the source of much debate and speculation amongst Christians for the past 2000 years.
In Revelation chapter 13, John describes two beasts; one rises out of the sea (Rev. 13:1-10), the other rises out of the earth (Rev. 13:11-18). Here is what it says about the second beast:
Then I saw another beast rising out of the earth. It had two horns like a lamb and it spoke like a dragon. It exercises all the authority of the first beast in its presence, and makes the earth and its inhabitants worship the first beast, whose mortal wound was healed. It performs great signs, even making fire come down from heaven to earth in front of people, and by the signs that it is allowed to work in the presence of the beast it deceives those who dwell on earth, telling them to make an image for the beast that was wounded by the sword and yet lived. And it was allowed to give breath to the image of the beast, so that the image of the beast might even speak and might cause those who would not worship the image of the beast to be slain. Also it causes all, both small and great, both rich and poor, both free and slave, to be marked on the right hand or the forehead, so that no one can buy or sell unless he has the mark, that is, the name of the beast or the number of its name. This calls for wisdom: let the one who has understanding calculate the number of the beast, for it is the number of a man, and his number is 666.Revelation 13:11-18
Throughout the years, Christians have tried to figure out what the Mark of the Beast is and what the number 666 means.
Adding fuel to the fears of a conspiracy is the fact that there is currently a bill before the House of Representatives numbered 6666, as well as a calculation of CORONA (6 letters in the word, and if you take the number of the order of the letters in the English alphabet, they add up to 66).
This isn’t the first time there have been rumors of the Mark of the Beast. Ronald Wilson Reagan (6 letters each = 6+6+6!) was accused of being the beast. Of course this is ridiculous for many reasons, not least of which is that it assumes that the Apostle John, who wrote in Greek, would give us a code which could only be deciphered in the English language (which did not even exist yet).
Many Bible scholars associate the number 666 with Caesar Nero, and there is good evidence for doing this. We know from Suetonius that many people were at the time toying with the numerical values of Nero’s name (Nero 39). This practice, known as gematria, took a letter of the alphabet and assigned it an equivalent number. So, for example, in the case of Greek, the first letter alpha would be given the number one. The second letter beta would be understood as two, and so on. When you take Nero’s name (Neron Kaisar) and transliterate it into Hebrew, the result is the number of the beast: 666. 
This doesn’t necessarily mean that the second beast in Revelation 13 was Nero; it could mean that it will be someone similar to or comparable to Nero.
The Mark of the Lamb?
What many people seem to forget when discussing the Mark of the Beast is that in the verses which immediately follow, the Mark of the Beast is juxtaposed with the Mark of the Lamb.
Perhaps some of you reading this have never even heard of the Mark of the Lamb. However, if we really desire to understand what the Mark of the Beast is, we have to understand it in light of the Mark of the Lamb.
Here’s what it says:
Then I looked, and behold, on Mount Zion stood the Lamb, and with him 144,000 who had his name and his Father’s name written on their foreheads. And I heard a voice from heaven like the roar of many waters and like the sound of loud thunder. The voice I heard was like the sound of harpists playing on their harps, and they were singing a new song before the throne and before the four living creatures and before the elders. No one could learn that song except the 144,000 who had been redeemed from the earth. It is these who have not defiled themselves with women, for they are virgins. It is these who follow the Lamb wherever he goes. These have been redeemed from mankind as firstfruits for God and the Lamb, and in their mouth no lie was found, for they are blameless.Revelation 14:1-5
This is referenced earlier in the book as well:
Then I saw another angel ascending from the rising of the sun, with the seal of the living God, and he called with a loud voice to the four angels who had been given power to harm earth and sea, saying, “Do not harm the earth or the sea or the trees, until we have sealed the servants of our God on their foreheads.”Revelation 7:2-3
So, any interpretation of what the Mark of the Beast is needs to consider that it must be something equal to and opposite of the Mark of the Lamb.
What are These Marks, and How Will You Know If You Have Them?
Considering how the Mark of the Beast is juxtaposed with the Mark of the Lamb, it seems clear that these two signs are identifiers, which identify your allegiance: either as person of the Dragon or as a person of the Lamb. It isn’t that you become a person of the Beast or the Lamb by receiving a mark, rather: the mark identifies you as what you already are. We see this in Revelation 7 & 14, where the mark given to God’s people is to identify them for who they already are, because they are already united to the Lamb.
In other words, these two marks are two opposite signs marking out two different types of people: the wicked and the righteous.
The Mark of the Beast is an identifier of loyalty and worship, and therefore is not something you could accidentally accept.
In the early 1980s, multiple books came out claiming that Uniform Product Codes (UPCs or “barcodes”) were the Mark of the Beast, since they were tied to buying and selling, with titles like: When Your Money Fails: The “666 System” is Here (1981) and The New Money System 666 (1982). In the late 80s and early 90s there were rumors that it could be something related to credit card companies. These ideas were predicated on the idea that the Mark of the Beast was something that could sneak up on you, and something you could accidentally use.
However, since the Mark of the Beast and the Mark of the Lamb are marks of loyalty and worship, a person will have full cognitive awareness of what they are doing (otherwise it is not worship). In other words, in order to take the Mark of the Beast, you would have to curse Christ and pledge devotion to his enemy – and it’s not something you could do on accident, or without realizing what you were doing.
In many countries, including the United States, it is almost impossible to function (think: buy or sell) without government-issued identification numbers, such as a Social Security Number or a Driver’s License Number. Almost everyone carries a mobile phone which contains a SIM card which can be tracked in different ways. Certain vaccines are required in order for children to attend public school. Whether these things are good or safe or whether the government has your best interest in mind may be valid points of discussion and consideration, but these things are not what the Mark of the Beast is about: it is about identification regarding allegiance and worship, and is therefore not something you can possibly receive against your will, desires, and full awareness of what you are doing.
Don’t Forget the Point of Revelation
It is important to remember that the revelation being given in the Book of Revelation is the revelation of Jesus (Rev. 1:1), not the revelation of the Beast!
The point and purpose of the book is not to make us scared about what the Beast is going to do, but to fill us with confidence because no matter what happens, Jesus is going to win!
Any interpretation of Revelation that results in “the beast” becoming the central focus (and dreaded fear) of your eschatology most definitely suggests that you’ve completely misunderstood the book entirely.Matthew L. Halstead, Ph.D.
Neither the Dragon nor the Beast are the “star of the show” in Revelation, but Jesus, who comes to defeat them and redeem His people.
Let us remember that Jesus is the Good Shepherd who told us this:
My sheep hear my voice, and I know them, and they follow me. I give them eternal life, and they will never perish, and no one will snatch them out of my hand. My Father, who has given them to me, is greater than all, and no one is able to snatch them out of the Father’s hand. I and the Father are one.”John 10:27-30
Whether you decide to receive a future vaccine or not is a decision for you to weigh and consider, but based on the clear teaching of the Bible, there is no need to fear that you will accidentally be taking the Mark of the Beast by doing so.
May we instead receive the mark and seal of the Lamb through heart-felt allegiance to Jesus, embracing the gospel whole-heartedly, with hope in the redemption He promises us, no matter what this life or any enemies may bring our way. This is the way of true security and confidence.